Article
An association study of angiotensinogen polymorphisms with serum level and hypertension in an African-American population.
Journal of hypertension - 1 Oct 2003
Wu Xiaodong, Luke Amy, Rieder Mark, Lee Kwok, Toth Emily J, Nickerson Deborah, Zhu Xiaofeng, Kan Donghui, Cooper Richard S
Abstract excerpt
OBJECTIVE: To evaluate the association of angiotensinogen (AGT) gene with AGT level and hypertension based on the overall genetic variation of the AGT gene in among African-Americans. METHODS: All non-rare single nucleotide polymorphisms (SNPs) in AGT were identified by resequencing 24 individuals. Five tagging SNPs were selected based on the pairwised linkage disequilibrium (LD) pattern and were genotyped in 284...
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