The molecular genetics of Huntington's disease.

doi:10.1097/00019052-199408000-00009

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Article

The molecular genetics of Huntington's disease.

Current opinion in neurology - 1 Aug 1994

Goldberg Y P, Telenius H, Hayden M R

Abstract excerpt

The past year has witnessed outstanding developments in research on Huntington's disease (HD). A gene was identified that contains an expanded CAG trinucleotide repeat on HD chromosomes. Patterns of expression of this gene and the nature of two transcripts were identified. CAG repeat size ranges...

Topics

Cell Death
Chromosomes, Human, Pair 4
Genetic Markers
Humans
Huntington Disease
Molecular Biology
Mutation
Pedigree
Repetitive Sequences, Nucleic Acid
Transcription Factors

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