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Article

Genetics and molecular biology of Huntington's disease.

Trends in neurosciences - 1 Jan 1995

Albin R L, Tagle D A

Abstract excerpt

In 1993, the genetic abnormality responsible for Huntington's disease was identified as a trinucleotide-repeat expansion in a novel gene. Much has been learned about the molecular genetics of Huntington's disease and the possible effects of the trinucleotide expansion in the development of this disease and other neurological disorders. The Huntington's disease locus is widely expressed throughout the brain and in...

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PMID: 7535483
DOI: 10.1016/0166-2236(95)93943-r

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