Huntington's disease.

doi:10.1016/1043-4682(95)90011-x

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Article

Huntington's disease.

Seminars in cell biology - 1 Feb 1995

Gusella J F, MacDonald M E

Abstract excerpt

Early in 1993, an unstable, expanded trinucleotide repeat in a novel gene of unknown function was identified on HD chromosomes. This discovery unleased a flurry of experimentation that has established the expanded CAG repeat the almost universal cause of the characteristic neurologic symptoms and...

Topics

Age of Onset
Alleles
Animals
DNA
Humans
Huntington Disease
Mutation
Repetitive Sequences, Nucleic Acid

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