Article
Molecular genetics of Alzheimer's disease.
Acta neurologica Scandinavica. Supplementum - 1 Jan 1996
Hardy J
Abstract excerpt
Four genes have thus far been implicated in the etiology of Alzheimer's disease (AD). A series of mutations in the amyloid precursor protein (APP) gene on chromosome 21, which cause disease with a typical onset of 55 years of age, have been described. These include mutations at APP670/671, APP692...
Topics
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- Apolipoproteins E
- Humans
- Mutation