Article
The yin and yang of p53 in cellular proliferation.
Seminars in cancer biology - 1 Jun 1994
Deppert W
Abstract excerpt
The tumor suppressor p53 is a key element in preserving the stability of the genetic information of vertebrates. In response to DNA damage, PSS induces a growth arrest thus allowing time for DNA repair to occur. However, p53 seems to exert additional functions in cellular proliferation, amongst t...
Topics
- Animals
- Base Sequence
- Cell Division
- DNA Replication
- Humans
- Molecular Sequence Data
- Mutation
- Repressor Proteins
- Transcriptional Activation
- Tumor Suppressor Protein p53