Article
The yin and yang of p53 in cellular proliferation.
Seminars in cancer biology - 1 Jun 1994
Deppert W
Abstract excerpt
The tumor suppressor p53 is a key element in preserving the stability of the genetic information of vertebrates. In response to DNA damage, PSS induces a growth arrest thus allowing time for DNA repair to occur. However, p53 seems to exert additional functions in cellular proliferation, amongst them a so far unidentified role in the progression of cells through the cell cycle and in differentiation processes....
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