Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 on the crossroad between regeneration and cancer

21 Oct 2016

Abstract excerpt

Regeneration and tumorigenesis share common molecular pathways, nevertheless the outcome of regeneration is life, whereas tumorigenesis leads to death. Although the process of regeneration is strictly controlled, malignant transformation is unrestrained. In this review, we discuss the involvement of TP53, the major tumor-suppressor gene, in the regeneration process. We point to the role of p53 as coordinator...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Liver physiology and pathology
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27768121
DOI: 10.1038/cdd.2016.117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 on the crossroad between regeneration and cancerPMID 27768121Read ↗

p53 balances between tissue hierarchy and anarchySemantic proximity Read ↗

p53 and its mutants on the slippery road from stemness to carcinogenesis.Semantic proximity Read ↗

Tumor suppressors: enhancers or suppressors of regeneration?Semantic proximity Read ↗

From tumor prevention to therapy: empowering p53 to fight back.Semantic proximity Read ↗

Normal and malignant growth control by p53.Semantic proximity Read ↗

p53 as the main traffic controller of the cell signaling network.Semantic proximity Read ↗

p53: at the crossroad between cancer and ageing.Semantic proximity Read ↗

p53 is balancing development, differentiation and de-differentiation to assure cancer preventionSemantic proximity Read ↗

Wild-type p53 in cancer cells: when a guardian turns into a blackguard.Semantic proximity Read ↗

Understanding the molecular mechanism of regeneration through apoptosis-induced compensatory proliferation studies - updates and future aspectsSemantic proximity Read ↗

The emerging role of p53 in stem cellsSemantic proximity Read ↗

Oncogenic Mutant p53 Gain of Function Nourishes the Vicious Cycle of Tumor Development and Cancer Stem-Cell Formation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.