Article
ALDH2 polymorphism and biological monitoring of toluene.
Archives of environmental health - 1 Jan 2000
Kawamoto T, Matsuno K, Kodama Y, Murata K, Matsuda S
Abstract excerpt
In this study, we evaluated the effects of the genetic polymorphism of ALDH2 (low Km aldehyde dehydrogenase) on toluene metabolism and determined biological exposure indices (BEIs) of the genotypes of ALDH2. The study subjects included 45 toluene workers and 122 nonexposed students. The genotype...
Topics
- Adult
- Aldehyde Dehydrogenase
- Environmental Monitoring
- Female
- Genotype
- Hippurates
- Humans
- Male
- Middle Aged
- Occupational Exposure
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Smoking
- Toluene