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Article

Modification of the relationship between urinary 8-OHdG and hippuric acid concentration by GSTM1, GSTT1, and ALDH2 genotypes.

Human & experimental toxicology - 1 Apr 2011

Kim Yong-Dae, Eom Sang-Yong, Zhang Yan Wei, Kim Hyeongsu, Park Jung-Duk, Yu Seung-Do, Lee Chul-Ho, Arashidani Keiichi, Kawamoto Toshihiro, Kim Heon

Abstract excerpt

Urinary hippuric acid (HA) has been widely used as a biological marker of occupational exposure to toluene, although it is no longer valid for low levels of toluene exposure. Toluene exposure is known to induce oxidative DNA damage and the metabolism is affected by genetic polymorphisms of some metabolizing enzymes. Therefore, genetic polymorphisms of these metabolizing enzymes must be considered in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20488846
DOI: 10.1177/0960327110371813

Genes

ALDH2
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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