Article
Biological monitoring of toluene and DNA polymorphism in humans.
International archives of occupational and environmental health - 1 Jan 1993
Kawamoto T, Matsuno K, Arashidani K, Yoshikawa M, Oyama T, Hattori Y, Kodama Y
Abstract excerpt
The effects of genetic polymorphism in aldehyde dehydrogenase 2 (ALDH2) on alcohol intakes and toluene metabolism were studied in workers who handle toluene. The genotypes of ALDH2 were divided into three groups, which were the homozygous genotype of normal ALDH2 (NN), the homozygous genotype of an inactive one (DD) and the heterozygous genotype of normal and inactive ones (ND), using the polymerase chain...
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