Article
ATP-dependent transport of organic anions in secretory vesicles of Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America - 27 Sept 1994
St-Pierre M V, Ruetz S, Epstein L F, Gros P, Arias I M
Abstract excerpt
Secretory mutants (sec1, sec6) of Saccharomyces cerevisiae accumulate large pools of secretory vesicles at the restrictive temperature (37 degrees C) because of a block in the delivery of vesicles to the cell surface. We report that secretory vesicles isolated from sec mutants exhibit ATP-dependent uptake of two classes of organic anions that are substrates for the canalicular carriers of mammalian liver....
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