Article
A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway.
The Journal of cell biology - 21 Jan 2002
Harsay Edina, Schekman Randy
Abstract excerpt
Exocytic vesicles that accumulate in a temperature-sensitive sec6 mutant at a restrictive temperature can be separated into at least two populations with different buoyant densities and unique cargo molecules. Using a sec6 mutant background to isolate vesicles, we have found that vacuolar protein sorting mutants that block an endosome-mediated route to the vacuole, including vps1, pep12, vps4, and a...
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