Article
Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast.
The Journal of cell biology - 10 Dec 2001
Funato K, Riezman H
Abstract excerpt
Transport and sorting of lipids must occur with specific mechanisms because the membranes of intracellular organelles differ in lipid composition even though most lipid biosynthesis begins in the ER. In yeast, ceramide is synthesized in the ER and transferred to the Golgi apparatus where inositolphosphorylceramide (IPC) is formed. These two facts imply that ceramide can be transported to the Golgi independent of...
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