The ORF1 of the gentamicin-resistance operon (aac) of Pseudomonas aeruginosa encodes adenosine 5'-phosphosulphate kinase.

doi:10.1111/j.1365-2958.1993.tb01251.x

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Article

The ORF1 of the gentamicin-resistance operon (aac) of Pseudomonas aeruginosa encodes adenosine 5'-phosphosulphate kinase.

Molecular microbiology - 1 Sept 1993

Satishchandran C, Taylor J C, Markham G D

Abstract excerpt

The gentamicin-resistance operon of Pseudomonas aeruginosa (aac) contains two cistrons for which only the second gene product has an identified function. The 813bp second cistron (ORF2) encodes a protein that confers gentamicin resistance by catalysis of the transfer of an acetyl group from acety...

Topics

Amino Acid Sequence
Drug Resistance, Microbial
Escherichia coli
Genes, Bacterial
Genetic Complementation Test
Gentamicins
Molecular Sequence Data
Open Reading Frames
Operon
Phenotype
Phosphotransferases (Alcohol Group Acceptor)
Plasmids
Pseudomonas aeruginosa
Sequence Homology, Amino Acid

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Open in PubMed

Identifiers

PMID: 7934935
DOI: 10.1111/j.1365-2958.1993.tb01251.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7934935-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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