Article
ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression.
Antimicrobial agents and chemotherapy - 1 Nov 2010
Zhang Ying, Bao Qiyu, Gagnon Luc A, Huletsky Ann, Oliver Antonio, Jin Shouguang, Langaee Taimour
Abstract excerpt
In enterobacteria, the ampG gene encodes a transmembrane protein (permease) that transports 1,6-GlcNAc-anhydro-MurNAc and the 1,6-GlcNAc-anhydro-MurNAc peptide from the periplasm to the cytoplasm, which serve as signal molecules for the induction of ampC β-lactamase. The role of AmpG as a transporter is also essential for cell wall recycling. Pseudomonas aeruginosa carries two AmpG homologues, AmpG (PA4393) and...
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