Article
Rapid accumulation of fluorescent material with aging in an oxygen-sensitive mutant mev-1 of Caenorhabditis elegans.
Mechanisms of ageing and development - 1 Jun 1994
Hosokawa H, Ishii N, Ishida H, Ichimori K, Nakazawa H, Suzuki K
Abstract excerpt
Mutations in mev-1 of the nematode Caenorhabditis elegans render animals hypersensitive to high oxygen concentrations. They also reduce life span. To further understand the effects of mev-1 on aging, accumulation of fluorescent material resembling lipofuscin was measured by biochemical and histological analyses. Fluorescent material accumulated in both wild type and mev-1 animals with increasing age. The mev-1...
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