Dose and dose-rate dependence of the frequency of HPRT deficient T lymphocytes in the spleen of the 137Cs gamma-irradiated mouse.

doi:10.1080/09553009414551251

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Article

Dose and dose-rate dependence of the frequency of HPRT deficient T lymphocytes in the spleen of the 137Cs gamma-irradiated mouse.

International journal of radiation biology - 1 Sept 1994

Lorenz R, Deubel W, Leuner K, Göllner T, Hochhäuser E, Hempel K

Abstract excerpt

The frequency of hypoxanthine phosphoribosyl transferase (HPRT) deficient splenic T lymphocytes was measured in the 137Cs gamma-irradiated mouse by the T cell cloning method. Doses from 0.3 to 6 Gy were applied at the dose-rates 0.5 Gy/min, 1 Gy/day and 1 Gy/week. Mutants were determined 8-10 and...

Topics

Animals
Cells, Cultured
Dose-Response Relationship, Radiation
Gamma Rays
Hypoxanthine Phosphoribosyltransferase
Male
Mice
Mice, Inbred C57BL
Mutation
Spleen
T-Lymphocytes

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