Article
Radiation dose-rate effect on mutation induction in spleen and liver of gpt delta mice.
Radiation research - 1 Feb 2010
Okudaira Naohito, Uehara Yoshihiko, Fujikawa Kazuo, Kagawa Nao, Ootsuyama Akira, Norimura Toshiyuki, Saeki Ken-ichi, Nohmi Takehiko, Masumura Ken-ichi, Matsumoto Tsuneya, Oghiso Yoichi, Tanaka Kimio, Ichinohe Kazuaki, Nakamura Shingo, Tanaka Satoshi, Ono Tetsuya
Abstract excerpt
The effect of dose rate on radiation-induced mutations in two somatic tissues, the spleen and liver, was examined in transgenic gpt delta mice. These mice can be used for the detection of deletion-type mutations, and these are the major type of mutation induced by radiation. The dose rates examin...
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