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Article

T cell repertoire in patients with B chronic lymphocytic leukemia. Evidence for multiple in vivo T cell clonal expansions.

1 Nov 1994

Abstract excerpt

To characterize circulating T cell subpopulations in B chronic lymphocytic leukemia patients, TCR V alpha and V beta gene-segment use was analyzed by PCR using a panel of V gene-segment subfamily-specific oligonucleotide primers (V alpha 1-29/V beta 1-24). Virtually all V alpha and V beta subfamily specificities were expressed in these patients (nine stage A and four stage C), and the mean values obtained for...

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Identifiers

PMID: 7930628
DOI: 10.4049/jimmunol.153.9.4281

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Source receipt: pubmed, retrieved 7 Sept 2026.

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