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Article

Characteristics of the TCR Vβ repertoire in imatinib-resistant chronic myeloid leukemia patients with ABL mutations.

Science China. Life sciences - 1 Dec 2015

Xu Ling, Lu YuHong, Lai Jing, Yu Wei, Zhang YiKai, Jin ZhenYi, Xu Yan, Chen Jie, Zha XianFeng, Chen ShaoHua, Yang LiJian, Li YangQiu

Abstract excerpt

Diversity in the T cell receptor (TCR) repertoire provides a miniature defense ability for the T cell immune system that may be related to tumor initiation and progression. Understanding the T cell immune status of leukemia patients is critical for establishing specific immunotherapies. Previous studies have reported abnormal TCR repertoires and clonally expanded TCR Vβ T cells in chronic myeloid leukemia in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Share to Receptors, Antigen, T-Cell, alpha-beta

Source

Identifiers

PMID: 26423566
DOI: 10.1007/s11427-015-4930-4

Genes

ABL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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