Article
Analysis of a Chinese population suggests that the TNFB gene is not a susceptibility gene for Graves' disease.
Human immunology - 1 Jun 1994
Cavan D A, Penny M A, Jacobs K H, Kelly M A, Jenkins D, Mijovic C H, Chow C C, Cockram C S, Hawkins B R, Barnett A H
Abstract excerpt
Graves' disease is associated with different HLA genes in different races. The TNFB gene lies between the class I and class II HLA genes and has two alleles, TNFB*1 and TNFB*2. Studies in Caucasians have suggested that the TNFB gene might be a susceptibility gene for Graves' disease. To investigate further the role of TNFB in predisposition to Graves' disease, we determined whether the TNFB disease associations...
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