Article
ras-family gene mutations in neoplasia of the ampulla of Vater.
International journal of cancer - 1 Oct 1994
Scarpa A, Zamboni G, Achille A, Capelli P, Bogina G, Iacono C, Serio G, Accolla R S
Abstract excerpt
Mutations in the first and second exons of Ha-, Ki- and N-ras oncogenes were investigated in 17 epithelial tumors of the ampulla of Vater by single-strand conformation polymorphism analysis and direct sequencing of DNA fragments amplified by polymerase chain reaction. The panel included 12 intest...
Topics
- Adenocarcinoma
- Adenoma
- Adult
- Aged
- Ampulla of Vater
- Base Sequence
- Carcinoma, Papillary
- Codon
- Common Bile Duct Neoplasms
- DNA, Neoplasm
- Exons
- Female
- Genes, ras
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
