Article
KRAS mutation as a prognostic factor in ampullary adenocarcinoma: a meta-analysis and review.
Oncotarget - 6 Sept 2016
Kim Bum Jun, Jang Hyun Joo, Kim Jung Han, Kim Hyeong Su, Lee Jin
Abstract excerpt
Ampullary adenocarcinoma (A-AC) is a rare malignancy arising from the ampulla of Vater. KRAS mutation is detected in 30-40% of patients with A-AC, but its clinical implication and prognostic value are not well described. We conducted this meta-analysis to investigate the association between KRAS mutation and prognosis in patients with A-AC. We searched Pubmed, MEDLINE, EMBASE, and the Cochrane Library databases...
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