K-ras mutation in adenomas and carcinomas of the ampulla of vater.

Article

K-ras mutation in adenomas and carcinomas of the ampulla of vater.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 1997

Howe J R, Klimstra D S, Cordon-Cardo C, Paty P B, Park P Y, Brennan M F

Abstract excerpt

The role of K-ras mutations in the progression of tumors of the ampulla of Vater is not well understood. To study the frequency and timing of K-ras mutations in ampullary tumors, areas of invasive carcinoma and adjacent adenomas were microdissected from paraffin blocks from 96 resected tumors. DN...

Topics

Adenoma
Ampulla of Vater
Carcinoma
Common Bile Duct Neoplasms
Genes, ras
Humans
Mutation
Time Factors

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