Article
[Gene p53 mutations and overexpression of p53 protein in tumors of the Vater's ampulla].
Gastroenterologie clinique et biologique - 1 May 1998
Terris B, Muzeau F, Sauvanet A, Belghiti J, Fléjou J F
Abstract excerpt
OBJECTIVES AND METHODS: New prognostic markers for tumors of the ampulla of Vater which could distinguish aggressive lesions would be highly useful. The aim of this study was to evaluate the abnormal expression of p53 protein in a series of 34 ampullomas with the monoclonal antibody DO7 directed...
Topics
- Adult
- Aged
- Ampulla of Vater
- Common Bile Duct Neoplasms
- Female
- Gene Expression Regulation, Neoplastic
- Genes, p53
- Humans
- Male
- Middle Aged
- Mutation
- Tumor Suppressor Protein p53
