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Article

Low incidence of KRAS, BRAF, and PIK3CA mutations in adenocarcinomas of the ampulla of Vater and their prognostic value.

Human pathology - 1 Apr 2016

Kwon Mi Jung, Kim Jeong Won, Jung Jae Pil, Cho Ji Woong, Nam Eun Sook, Cho Seong Jin, Kim Joo Seop, Park Hye-Rim, Min Soo Kee, Seo Jinwon, Min Kyueng-Whan, Kim Dong Hoon, Jeon Jang Yong

Abstract excerpt

Ampullary adenocarcinomas (A-ACs) are rare malignancies with considerable importance because of their high curable resection rate and improved survival rate among periampullary cancers. The RAS-RAF-MAPK pathway is involved in the development of A-ACs and is a potential therapeutic target. However, molecular profiles of A-ACs and their prognostic impact are poorly understood. Peptide nucleic acid-mediated...

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Identifiers

PMID: 26997442
DOI: 10.1016/j.humpath.2015.11.009

Genes

KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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