Article
Deep-sequencing analysis of the association between the quasispecies nature of the hepatitis C virus core region and disease progression.
Journal of virology - 1 Dec 2013
Miura Mika, Maekawa Shinya, Takano Shinichi, Komatsu Nobutoshi, Tatsumi Akihisa, Asakawa Yukiko, Shindo Kuniaki, Amemiya Fumitake, Nakayama Yasuhiro, Inoue Taisuke, Sakamoto Minoru, Yamashita Atsuya, Moriishi Kohji, Enomoto Nobuyuki
Abstract excerpt
Variation of core amino acid (aa) 70 of hepatitis C virus (HCV) has been shown recently to be closely correlated with liver disease progression, suggesting that the core region might be present as a quasispecies during persistent infection and that this quasispecies nature might have an influence...
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