Article
The role of the CCA sequence of tRNA in the peptidyl transfer reaction.
FEBS letters - 17 Oct 1994
Tamura K
Abstract excerpt
Peptidyl transfer is a key step in the process of protein biosynthesis. To examine the role of the universal CCA terminal sequence of tRNA in the process of peptidyl transfer, various mutant transcripts of Escherichia coli valine tRNA were constructed. Peptidyl transferase activity, monitored by the 'fragment reaction' with a slight modification, was decreased by mutation at any one base of CCA. The effect of...
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