Article
Phosphorylation of a proline-directed kinase motif is responsible for structural changes in myogenin.
FEBS letters - 26 Sept 1994
Hashimoto N, Ogashiwa M, Okumura E, Endo T, Iwashita S, Kishimoto T
Abstract excerpt
Myogenin, a member of the MyoD family which governs skeletal muscle differentiation, was identified as a pair of phosphorylated bands on SDS-PAGE during myogenesis. The slow migrating form was found to be hyperphosphorylated myogenin. In vitro phosphorylation by CDC2 kinase caused a prominent red...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Differentiation
- Cell Line
- Gene Expression
- Molecular Sequence Data
- Muscle, Skeletal
- Mutation
- Myogenin
- Peptide Fragments
- Peptides
- Phosphopeptides
- Phosphorylation
- Proline-Directed Protein Kinases
- Protein Serine-Threonine Kinases
- Serine
- Transfection