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Article

Phosphorylation of a proline-directed kinase motif is responsible for structural changes in myogenin.

FEBS letters - 26 Sept 1994

Hashimoto N, Ogashiwa M, Okumura E, Endo T, Iwashita S, Kishimoto T

Abstract excerpt

Myogenin, a member of the MyoD family which governs skeletal muscle differentiation, was identified as a pair of phosphorylated bands on SDS-PAGE during myogenesis. The slow migrating form was found to be hyperphosphorylated myogenin. In vitro phosphorylation by CDC2 kinase caused a prominent reduction in electrophoretic mobility of myogenin. Furthermore, we demonstrated that phosphorylation of the serine residue...

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PMID: 7925980
DOI: 10.1016/0014-5793(94)00964-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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