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Article

High relative frequency of SCA1 in Poland reflecting a potential founder effect.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Aug 2016

Krysa Wioletta, Sulek Anna, Rakowicz Maria, Szirkowiec Walentyna, Zaremba Jacek

Abstract excerpt

Spinocerebellar ataxias (SCAs) have irregular distributions worldwide. SCA1 is the most frequent in Poland, and no cases of SCA3 of Polish origin has yet been identified. In view of such patterns of SCAs occurrence, the relative frequency, geographical distribution and a possible founder effect of SCA1 were investigated. DNA samples of 134 probands with SCA1 and 228 controls were analysed. The genotyping of four...

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Identifiers

PMID: 27193757
DOI: 10.1007/s10072-016-2594-x
PMCID: PMC4956719

Genes

ATXN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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