Article
FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations.
Cell - 23 Sept 1994
Hébert J M, Rosenquist T, Götz J, Martin G R
Abstract excerpt
Fibroblast growth factor 5 (FGF5) is a secreted signaling protein. Mice homozygous for a predicted null allele of the Fgf5 gene, fgf5neo, produced by gene targeting in embryonic stem cells, have abnormally long hair. This phenotype appears identical to that of mice homozygous for the spontaneous...
Topics
- Alleles
- Animals
- Base Sequence
- Fibroblast Growth Factor 5
- Fibroblast Growth Factors
- Genetic Complementation Test
- Hair
- Homozygote
- In Situ Hybridization
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Mutant Strains
- Molecular Sequence Data
- Phenotype
- RNA, Messenger
- Tissue Distribution