Article
FGF5.
Differentiation; research in biological diversity - 1 Jan 2000
Carrion Evelyn A, Moses Malcolm M, Behringer Richard R
Abstract excerpt
FGF5 functions as a negative regulator of the hair cycle in mammals. It is expressed in the outer root sheath of hair follicles during the late anagen phase of the hair cycle. It functions as a signaling molecule, mediating the transition of the anagen growth phase to catagen regression phase of the hair cycle. Spontaneous and engineered FGF5 mutations in mammalian animal models result in long hair phenotypes. In...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.