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Article

Gender-Difference in Hair Length as Revealed by Crispr-Based Production of Long-Haired Mice with Dysfunctional FGF5 Mutations.

International journal of molecular sciences - 6 Oct 2022

Takahashi Ryo, Takahashi Gou, Kameyama Yuichi, Sato Masahiro, Ohtsuka Masato, Wada Kenta

Abstract excerpt

Fibroblast growth factor 5 (FGF5) is an important molecule required for the transition from anagen to catagen phase of the mammalian hair cycle. We previously reported that Syrian hamsters harboring a 1-bp deletion in the Fgf5 gene exhibit excessive hair growth in males. Herein, we generated Fgf5 mutant mice using genome editing via oviductal nucleic acid delivery (GONAD)/improved GONAD (i-GONAD), an in vivo...

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Identifiers

PMID: 36233155
DOI: 10.3390/ijms231911855
PMCID: PMC9569730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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