Article
Immune-escape markers in relation to clinical outcome of advanced melanoma patients following immunotherapy.
Cancer immunology research - 1 Jun 2014
Tjin Esther P M, Krebbers Gabrielle, Meijlink Kimberley J, van de Kasteele Willeke, Rosenberg Efraim H, Sanders Joyce, Nederlof Petra M, van de Wiel Bart A, Haanen John B A G, Melief Cornelis J M, Vyth-Dreese Florry A, Luiten Rosalie M
Abstract excerpt
In this study, we investigated a large series of immune (escape) markers, relevant to T-cell function, as potential biomarkers for clinical outcome following immunotherapy. We retrospectively studied the expression of immune (escape) markers in metastatic melanoma tissues of 27 patients before autologous tumor cell vaccination, and 16 patients who were intended to treat but were not vaccinated because of rapid...
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