Article
The repertoire of antibodies to a hapten group in an inbred strain of mouse.
La Ricerca in clinica e in laboratorio - 1 Jan 2000
Ju S T, Nisonoff A
Abstract excerpt
We have investigated the diversity of antibodies to the p-azophenylarsonate (Ar) hapten group in the A strain of mouse. The method used consisted of suppressing an idiotype which commonly is observed in the anti-Ar antibodies of all this strain, and then generating anti-idiotypic antisera against the anti-Ar antibodies (lacking the cross-reactive idiotype) which arose after hyperimmunization of the suppressed...
Topics
- Animals
- Antibody Formation
- Antibody Specificity
- Azo Compounds
- Cross Reactions
- Epitopes
- Immune Sera
- Isoelectric Focusing
- Mice
- Mice, Inbred A
- Mutation
- Radioimmunoassay
