Article
Lack of association between a polymorphism of human thyrotropin receptor gene and autoimmune thyroid disease.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Dec 1999
Sunthornthepvarakul T, Kitvitayasak S, Ngowngarmaratana S, Konthong P, Deerochanawong C, Sarinnapakorn V, Phongviratchai S
Abstract excerpt
A polymorphism in codon 52 of the human thyrotropin receptor results in a proline to threonine substitution in the extracellular domain of the receptor, but the association with autoimmune thyroid disease has been uncertain and there is no report the prevalence of this polymorphism in Orientals. To investigate this polymorphism and the association with autoimmune thyroid disease, we studied 113 normal unrelated...
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