Article
The retinal Schiff base-counterion complex of bacteriorhodopsin: changed geometry during the photocycle is a cause of proton transfer to aspartate 85.
Biochemistry - 11 Oct 1994
Brown L S, Gat Y, Sheves M, Yamazaki Y, Maeda A, Needleman R, Lanyi J K
Abstract excerpt
Bacteriorhodopsin contains all-trans-retinal linked via a protonated Schiff base to K216. The proton transport in this pump is initiated by all-trans to 13-cis photoisomerization of the retinal and the ensuing transfer of the Schiff base proton to D85. Changed geometrical relationship of the Schiff base and D85 after the photoisomerization is a possible reason for the proton transfer. We introduced small...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.