Article
Properties of tyrosine 766-->serine mutant of Escherichia coli DNA polymerase I: template-specific effects.
Biochemistry - 4 Oct 1994
Desai S D, Pandey V N, Modak M J
Abstract excerpt
In order to determine the role of Tyr 766 of Escherichia coli DNA polymerase I in the catalysis of DNA synthesis, we investigated the properties of a Tyr 766-->Ser (Y766S) mutant of the Klenow fragment of E. coli DNA polymerase I. We found that the rates of incorporation of only dTTP but not the...
Topics
- Base Sequence
- DNA
- DNA Adducts
- DNA Polymerase I
- DNA Primers
- Deoxyguanine Nucleotides
- Deoxyribonucleotides
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Serine
- Substrate Specificity
- Thymine Nucleotides
- Tyrosine
- Ultraviolet Rays