Article
A region of primer binding variation at the D6S265 locus associated with HLA-A25 and HLA-A26 antigens.
Human genetics - 1 Oct 1995
Pyper W, Burt M, Powell L, Webb S, Adès L, Halliday J, Jazwinska E
Abstract excerpt
D6S265 is a polymorphic dinucleotide repeat, mapped within 70 kb centromeric of HLA-A, on chromosome 6p21.3. While genotyping families for genetic linkage analysis, allele non-amplification resulting in apparent non-Mendelian inheritance was observed at the D6S265 locus in 15 individuals, on chromosomes carrying the HLA-A25 and HLA-A26 antigens. The D6S265 locus was sequenced in a variant individual homozygous...
Topics
- Base Sequence
- DNA Primers
- DNA, Satellite
- Genetic Linkage
- Genetic Variation
- Genotype
- HLA-A Antigens
- Humans
- Molecular Sequence Data