Article
Critical phosphorylation sites for acetyl-CoA carboxylase activity.
The Journal of biological chemistry - 2 Sept 1994
Ha J, Daniel S, Broyles S S, Kim K H
Abstract excerpt
Acetyl-CoA carboxylase (ACC) is rapidly regulated by reversible phosphorylation; phosphorylation inactivates ACC, whereas dephosphorylation activates the enzyme. Among protein kinases only cAMP-dependent protein kinase and 5'-AMP-dependent protein kinase can inactivate ACC; cAMP-dependent protein kinase phosphorylates Ser-77 and -1200; 5'-AMP-dependent protein kinase phosphorylates Ser-79, -1200, and -1215. In...
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