Article
Cooperative association of T cell beta receptor and HLA-DQ alleles in the production of anti-Ro in systemic lupus erythematosus.
Clinical immunology and immunopathology - 1 Sept 1994
Scofield R H, Frank M B, Neas B R, Horowitz R M, Hardgrave K L, Fujisaku A, McArthur R, Harley J B
Abstract excerpt
The immunogenetics of the autoantibody response to Ro (or SS-A) have been explored in patients with systemic lupus erythematous. Data show that alleles of the T cell beta receptor and HLA-DQ loci are cooperatively associated with the presence of anti-Ro autoantibodies in systemic lupus erythemato...
Topics
- Alleles
- Antibodies, Antinuclear
- Autoantigens
- Blotting, Southern
- HLA-DQ Antigens
- Humans
- Lupus Erythematosus, Systemic
- Polymorphism, Restriction Fragment Length
- RNA, Small Cytoplasmic
- Receptors, Antigen, T-Cell, alpha-beta
- Ribonucleoproteins