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Article

HLA in ankylosing spondylitis: is HLA-B27 the only MHC gene involved in disease pathogenesis?

Seminars in arthritis and rheumatism - 1 Apr 1994

Reveille J D, Suarez Almazor M E, Russell A S, Go R C, Appleyard J, Barger B O, Acton R T, Koopman W J, McDaniel D O

Abstract excerpt

Linkage analysis of HLA haplotypes, HLA-B27 subtypes, and a 9.2-kb PvuII B7 restriction fragment length polymorphism (RFLP) (shown previously to be associated with peripheral arthritis in ankylosing spondylitis [AS]) in 115 relatives from 12 multiplex spondyloarthropathy (SNSA) and 2 B27-positive control families showed AS to be linked to HLA-B27 haplotypes. The RFLP segregated with HLA-A3- and HLA-A9-bearing...

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PMID: 7913556
DOI: 10.1016/0049-0172(94)90026-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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HLA in ankylosing spondylitis: is HLA-B27 the only MHC gene involved in disease pathogenesis?PMID 7913556Read ↗

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HLA-B27 alone rather than B27-related class I haplotypes contributes to ankylosing spondylitis susceptibility.Semantic proximity Read ↗

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Genetic aspects of ankylosing spondylitis.Semantic proximity Read ↗

The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis.Semantic proximity Read ↗

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