Article
HLA-B27 homozygosity has no influence on clinical manifestations and functional disability in ankylosing spondylitis.
Clinical and experimental rheumatology - 1 Jan 2000
Kim T-J, Na K-S, Lee H-J, Lee B, Kim T-H
Abstract excerpt
OBJECTIVE: There is an established association between the development of ankylosing spondylitis (AS) and the HLA-B27 allele, but whether or not homozygosity for HLA B27 has any additional effects on the clinical manifestations of AS is unclear. The aim of this study was to determine the influence of HLA-B27 homozygosity on the clinical manifestations of AS in Korea. METHODS: A total of 490 patients were enrolled...
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