Article
Non-B27 MHC associations of ankylosing spondylitis.
Genes and immunity - 1 Mar 2007
Sims A-M, Barnardo M, Herzberg I, Bradbury L, Calin A, Wordsworth B P, Darke C, Brown M A
Abstract excerpt
Ankylosing spondylitis (AS) has been associated with human leukocyte antigen (HLA)-B27 for over 30 years; however, the mechanism of action has remained elusive. Although many studies have reported associations between AS and other genes in the major histocompatibility complex (MHC) in AS, no conclusive results have emerged. To investigate the contribution of non-B27 MHC genes to AS, a large cohort of AS families...
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