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Article

NF-κ B-Dependent and -Independent Pathways of HIV Activation in a Chronically Infected T Cell Line

1 Aug 1994

Abstract excerpt

J delta K cells were isolated as a chronically infected survivor cell line, following infection of Jurkat CD4+ T cells with dl-NF, a mutated strain of human immunodeficiency virus type 1 (HIV-1) containing a deletion of the long terminal repeat (LTR) NF-kappa B sites. J delta K cells exhibited very low levels of constitutive HIV production. HIV-1 expression was activated from J delta K cells by treatment with...

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Identifiers

PMID: 7913275
DOI: 10.1006/viro.1994.1390

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