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NF-κB-Dependent Production of ROS and Restriction of HSV-1 Infection in U937 Monocytic Cells

10 May 2019

Abstract excerpt

Herpes simplex virus 1 (HSV-1) can infect a wide range of cell types, including cells of the adaptive and innate immunity but, normally, it completes a fully-permissive replication cycle only in epithelial or neural cells. Complex mechanisms controlling this delicate balance in immune cells and consequent restriction of HSV-1 infection in these cells have not been completely elucidated. We have recently...

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PMID: 31083280
DOI: 10.3390/v11050428

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