Current perspectives on the diagnosis and management of patients with multiple endocrine neoplasia type 2 syndromes.

Article

Current perspectives on the diagnosis and management of patients with multiple endocrine neoplasia type 2 syndromes.

Endocrinology and metabolism clinics of North America - 1 Mar 1994

Wells S A, Donis-Keller H

Abstract excerpt

Patients with MEN 2A, MEN 2B, and familial non-MEN medullary thyroid carcinoma (MTC) inherit MTC in an autosomal dominant fashion. This malignancy has been diagnosed previously by detecting elevated plasma calcitonin levels, a tumor marker for MTC, following the intravenous administration of secr...

Topics

DNA, Neoplasm
Genetic Linkage
Genetic Testing
Humans
Multiple Endocrine Neoplasia
Mutation
Proto-Oncogene Mas
Risk Factors
Sensitivity and Specificity
Thyroid Neoplasms

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