Treatment of minute medullary thyroid carcinoma in multiple endocrine neoplasia 2A families first diagnosed by DNA analysis of RET proto-oncogene mutations: a case report.

doi:10.1093/jjco/27.1.42

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Article

Treatment of minute medullary thyroid carcinoma in multiple endocrine neoplasia 2A families first diagnosed by DNA analysis of RET proto-oncogene mutations: a case report.

Japanese journal of clinical oncology - 1 Feb 1997

Yamashita T, Lihara M, Okamoto J, Kanbe M, Ito Y, Kawakami M, Egawa S, Yamaguchi K, Obara T

Abstract excerpt

Multiple endocrine neoplasia (MEN) 2A is an inherited disease characterized by the development of medullary thyroid carcinoma, pheochromocytoma and hyperparathyroidism. It has recently been shown to be associated with germ-line mutations in the RET proto-oncogene. We describe a 21-year-old man fr...

Topics

Adrenal Gland Neoplasms
Adult
Carcinoma, Medullary
DNA, Neoplasm
Drosophila Proteins
Family Health
Humans
Hyperparathyroidism
Male
Multiple Endocrine Neoplasia Type 2a
Mutation
Pheochromocytoma
Proto-Oncogene Mas
Proto-Oncogene Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins c-ret

Receptor Protein-Tyrosine Kinases

Thyroid Neoplasms

Thyroidectomy

Source

Open in PubMed

Identifiers

PMID: 9070340
DOI: 10.1093/jjco/27.1.42

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9070340-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.