Article
Gem: an induced, immediate early protein belonging to the Ras family.
Science (New York, N.Y.) - 8 Jul 1994
Maguire J, Santoro T, Jensen P, Siebenlist U, Yewdell J, Kelly K
Abstract excerpt
A gene encoding a 35-kilodalton guanosine triphosphate (GTP)-binding protein, Gem, was cloned from mitogen-induced human peripheral blood T cells. Gem and Rad, the product of a gene overexpressed in skeletal muscle in individuals with Type II diabetes, constitute a new family of Ras-related GTP-binding proteins. The distinct structural features of this family include the G3 GTP-binding motif, extensive amino- and...
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