Article
Relationship between DQ alpha and DQ beta RFLP and cell surface polymorphisms of class II HLA antigens.
Journal of immunogenetics - 1 Jan 2000
Cascino I, Rosenshine S, Turco E, Marrari M, Duquesnoy R J, Trucco M
Abstract excerpt
DQ alpha and beta DNA probes of the human major histocompatibility complex (MHC) were hybridized to restriction enzyme-digested genomic DNA with the aim of establishing a correspondence between the polymorphisms recognized by classical serology and DNA restriction fragment length polymorphisms (RFLP). In DR homozygous human cell lines, three distinct PstI fragments were recognized by the DQ alpha probe and four...
Topics
- Alleles
- Cell Line
- Gene Frequency
- HLA-D Antigens
- HLA-DQ Antigens
- HLA-DR Antigens
- Homozygote
- Humans
- Lymphocytes
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
